Lowe was a Pulitzer Prize finalist in 1990. He has won many awards for his work, including a 1996 John Fischetti Award and the 1992 Green Eyeshade Award. His cartoons have appeared in the national publications of Newsweek, The New York Times, The Washington Post, and on network television. He was commissioned to design a poster by the Library of Congress in Washington, D.C. He also illustrated the humor book, Are You a Newrotic (Prentice-Hall). A kinetic sculpture by Lowe was exhibited in 1997 at the National Gallery for Caricature and Cartoon Art in Washington.

In 1992, Lowe spent a year studying at Stanford University as a John S. Knight Journalism Fellow.

A resident of Palm Beach County, Florida, Lowe's interests include history, sailing, woodworking and playing the Baroque flute.